SCHEMBL23766403

SCHEMBL23766403

CCCCN1C(=O)/C(=C/c2c[nH]c3ccccc23)C(=O)N1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.56
KMT2A Q03164 8/20 0.56
MEN1 O00255 6/20 0.56
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 4/20 0.48
LMNA P02545 2/20 0.48
HPGD P15428 1/20 0.48
NTRK1 P04629 2/20 0.45
RET P07949 2/20 0.45
DAPK3 O43293 1/20 0.45
PRKD3 O94806 1/20 0.45
MAP4K4 O95819 1/20 0.45
ABL1 P00519 1/20 0.45
LCK P06239 1/20 0.45
FYN P06241 1/20 0.45
CSF1R P07333 1/20 0.45
PDGFRB P09619 1/20 0.45
PDGFRA P16234 1/20 0.45
LTK P29376 1/20 0.45
GRK5 P34947 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24251278 1.00 MAPT (0.56) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL24251255 0.96 MAPT (0.59) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL24251256 0.85 MAPT (0.60) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL26277408 0.80 MAPT (0.52) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL22923966 0.78 KDM4E (0.43) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL24251269 0.78 KDM4E (0.43) KDM4EALDH1A1HPGDNPC1RAB9A
SCHEMBL19820158 0.77 MAPT (0.57) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL24251263 0.75 KMT2A (0.67) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL22924023 0.75 MAPT (0.47) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL24943514 0.74 KDM4E (0.46) KDM4EALDH1A1HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021162115-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE 富士フイルム株式会社 2021-08-19 WO disclosed