Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.60 |
| ▸ | GSPT1 | P15170 | 3/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21069442 | 0.99 | CRBN (0.61) | CRBNDDB1GSPT1PDE3BPDE3A | |
| SCHEMBL22502645 | 0.93 | CRBN (0.60) | CRBNDDB1GSPT1TRIM24 | |
| SCHEMBL21069660 | 0.93 | CRBN (0.60) | CRBNDDB1GSPT1TRIM24 | |
| SCHEMBL21070391 | 0.93 | CRBN (0.60) | CRBNDDB1GSPT1TRIM24 | |
| SCHEMBL22526536 | 0.91 | CRBN (0.62) | CRBNDDB1GSPT1 | |
| SCHEMBL23842131 | 0.91 | CRBN (0.67) | CRBNDDB1GSPT1 | |
| SCHEMBL21997747 | 0.90 | CRBN (0.59) | CRBNDDB1GSPT1 | |
| SCHEMBL24764861 | 0.90 | DDB1 (0.65) | CRBNDDB1TRIM24 | |
| SCHEMBL21070141 | 0.90 | DDB1 (0.65) | CRBNDDB1TRIM24 | |
| SCHEMBL23842050 | 0.90 | CRBN (0.66) | CRBNDDB1GSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162493-A1 | PROTEIN KINASE DEGRADATION INDUCING COMPOUND, AND USE THEREOF | 보로노이 주식회사 | 2021-08-19 | — | — | WO | disclosed |