Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL1B | P01584 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31277149 | 0.99 | CRBN (0.56) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31277446 | 0.97 | CRBN (0.56) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31277498 | 0.94 | CRBN (0.58) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL28364556 | 0.92 | CRBN (0.56) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL28360919 | 0.92 | CRBN (0.56) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL28364637 | 0.92 | CRBN (0.56) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL28364532 | 0.91 | CRBN (0.57) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL23575670 | 0.90 | CRBN (0.58) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL25507852 | 0.90 | CRBN (0.55) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL25287767 | 0.89 | CRBN (0.59) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162493-A1 | PROTEIN KINASE DEGRADATION INDUCING COMPOUND, AND USE THEREOF | 보로노이 주식회사 | 2021-08-19 | — | — | WO | disclosed |