Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 11/20 | 0.51 |
| ▸ | BTK | Q06187 | 7/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23768895 | 1.00 | KLKB1 (0.51) | KLKB1BTKPDE10AGRM2 | |
| SCHEMBL29906541 | 1.00 | KLKB1 (0.51) | KLKB1BTKPDE10AGRM2 | |
| SCHEMBL29906663 | 1.00 | KLKB1 (0.51) | KLKB1BTKPDE10AGRM2 | |
| SCHEMBL23769384 | 1.00 | KLKB1 (0.51) | KLKB1BTKPDE10AGRM2 | |
| SCHEMBL23768899 | 1.00 | KLKB1 (0.51) | KLKB1BTKPDE10AGRM2 | |
| SCHEMBL26311371 | 0.94 | KLKB1 (0.51) | KLKB1BTKPDE10AGRM2 | |
| SCHEMBL23843047 | 0.91 | KLKB1 (0.49) | KLKB1BTKPDE10AGRM2 | |
| SCHEMBL23769682 | 0.91 | KLKB1 (0.49) | KLKB1BTKPDE10AGRM2 | |
| SCHEMBL23773103 | 0.91 | KLKB1 (0.60) | KLKB1BTKGRM2 | |
| SCHEMBL23769173 | 0.88 | KLKB1 (0.52) | KLKB1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |