Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978853 | 0.89 | MAPT (0.56) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL23769036 | 0.89 | MAPT (0.56) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL30248448 | 0.82 | MAPT (0.52) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL25028529 | 0.82 | MAPT (0.52) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL23768827 | 0.81 | MAPT (0.49) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL29227011 | 0.80 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL29227188 | 0.80 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL25028042 | 0.80 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL29227209 | 0.80 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL30248409 | 0.80 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161230-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2021-08-19 | — | — | WO | disclosed |