Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23769003 | 0.90 | SMN1; SMN2 (0.37) | CCR3SMN1; SMN2HTTMEN1MAPT | |
| SCHEMBL23769086 | 0.89 | SMN1; SMN2 (0.37) | CCR3SMN1; SMN2HTTMEN1MAPT | |
| SCHEMBL29978520 | 0.88 | SMN1; SMN2 (0.37) | CCR3SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL23769118 | 0.88 | SMN1; SMN2 (0.37) | CCR3SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL29978502 | 0.77 | HTT (0.39) | CCR3SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL25138429 | 0.77 | HTT (0.39) | CCR3SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL23769120 | 0.76 | HTT (0.36) | SMN1; SMN2HTTRAB9ANPC1RIPK1 | |
| SCHEMBL23769122 | 0.76 | SMN1; SMN2 (0.38) | CCR3SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL29978800 | 0.76 | SMN1; SMN2 (0.38) | CCR3SMN1; SMN2HTTRAB9ANPC1 | |
| SCHEMBL23769066 | 0.74 | CCR3 (0.36) | CCR3SMN1; SMN2HTTNPY1RMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161230-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2021-08-19 | — | — | WO | disclosed |