Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23769299 | 0.94 | KLKB1 (0.39) | KLKB1NPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL23843121 | 0.89 | KLKB1 (0.46) | KLKB1NPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL23768961 | 0.86 | KLKB1 (0.38) | KLKB1NPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL23769338 | 0.82 | KLKB1 (0.47) | KLKB1NPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL23769289 | 0.81 | KLKB1 (0.48) | KLKB1NPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL23769294 | 0.80 | KLKB1 (0.47) | KLKB1NPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL23769231 | 0.79 | KLKB1 (0.47) | KLKB1KDM4E | |
| SCHEMBL23769181 | 0.78 | KLKB1 (0.49) | KLKB1NPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL23843064 | 0.78 | KLKB1 (0.49) | KLKB1NPC1RAB9AKDM4ERXFP1 | |
| SCHEMBL21736650 | 0.78 | KLKB1 (0.49) | KLKB1NPC1RAB9AKDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |