Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29906632 | 0.85 | KLKB1 (0.48) | KLKB1 | |
| SCHEMBL23830201 | 0.85 | KLKB1 (0.48) | KLKB1 | |
| SCHEMBL23769739 | 0.78 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL23769476 | 0.77 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL23843184 | 0.77 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL23843250 | 0.73 | KLKB1 (0.48) | KLKB1 | |
| SCHEMBL23769522 | 0.72 | KLKB1 (0.65) | KLKB1 | |
| SCHEMBL23768974 | 0.71 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL23769548 | 0.71 | KLKB1 (0.65) | KLKB1 | |
| SCHEMBL23769458 | 0.71 | KLKB1 (0.54) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |