Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 13/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23843122 | 1.00 | BTK (0.46) | BTKKLKB1RET | |
| SCHEMBL23769689 | 0.90 | BTK (0.48) | BTKKLKB1 | |
| SCHEMBL23843098 | 0.89 | BTK (0.49) | BTKKLKB1 | |
| SCHEMBL18816600 | 0.88 | BTK (0.58) | BTKKLKB1 | |
| SCHEMBL21713103 | 0.86 | KLKB1 (0.46) | BTKKLKB1RET | |
| SCHEMBL31033231 | 0.85 | KLKB1 (0.57) | BTKKLKB1 | |
| SCHEMBL20540770 | 0.85 | KLKB1 (0.57) | BTKKLKB1 | |
| SCHEMBL29906586 | 0.84 | KLKB1 (0.45) | BTKKLKB1 | |
| SCHEMBL23754342 | 0.84 | KLKB1 (0.45) | BTKKLKB1 | |
| SCHEMBL23769206 | 0.84 | KLKB1 (0.49) | BTKKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |