Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23843138 | 0.83 | HTT (0.44) | KLKB1 | |
| SCHEMBL23769367 | 0.82 | NPC1 (0.34) | KLKB1 | |
| SCHEMBL23769139 | 0.75 | KLKB1 (0.40) | KLKB1 | |
| SCHEMBL23769540 | 0.73 | KLKB1 (0.34) | KLKB1 | |
| SCHEMBL23769466 | 0.72 | KLKB1 (0.32) | KLKB1 | |
| SCHEMBL23843235 | 0.72 | KLKB1 (0.33) | KLKB1 | |
| SCHEMBL23769176 | 0.71 | PTGER2 (0.35) | KLKB1 | |
| SCHEMBL23769538 | 0.71 | KLKB1 (0.33) | KLKB1 | |
| SCHEMBL23754304 | 0.70 | KLKB1 (0.35) | KLKB1 | |
| SCHEMBL23754303 | 0.70 | KLKB1 (0.35) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |