Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23769736 | 0.89 | KLKB1 (0.58) | KLKB1 | |
| SCHEMBL29906589 | 0.89 | KLKB1 (0.58) | KLKB1 | |
| SCHEMBL23769485 | 0.88 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL23769461 | 0.88 | KLKB1 (0.58) | KLKB1 | |
| SCHEMBL23769671 | 0.87 | KLKB1 (0.65) | KLKB1 | |
| SCHEMBL23769489 | 0.87 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL23769482 | 0.87 | KLKB1 (0.57) | KLKB1 | |
| SCHEMBL23769521 | 0.87 | KLKB1 (0.70) | KLKB1 | |
| SCHEMBL23843073 | 0.86 | KLKB1 (0.56) | KLKB1 | |
| SCHEMBL23769674 | 0.86 | KLKB1 (0.59) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |