Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 18/20 | 0.47 |
| ▸ | CCNK | O75909 | 18/20 | 0.47 |
| ▸ | CDK9 | P50750 | 18/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 18/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 15/20 | 0.47 |
| ▸ | CDK2 | P24941 | 15/20 | 0.47 |
| ▸ | CDK7 | P50613 | 7/20 | 0.41 |
| ▸ | CCNH | P51946 | 7/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.41 |
| ▸ | IL1B | P01584 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29464500 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL19925039 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL19925037 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL29464462 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL19925751 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| SCHEMBL23770823 | 0.80 | CYP1A2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL19951376 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Hydrochloric Acid SCHEMBL19925784 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Hydrochloric Acid SCHEMBL29464926 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 | |
| Hydrochloric Acid SCHEMBL29464914 | 0.80 | CCNT1 (0.47) | CCNT1CCNKCDK9CDK12CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |