Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.54 |
| ▸ | RET | P07949 | 7/20 | 0.52 |
| ▸ | MET | P08581 | 5/20 | 0.45 |
| ▸ | RIPK3 | Q9Y572 | 4/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | MST1R | Q04912 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749307 | 0.90 | KDR (0.54) | KDRRETMETRIPK3RIPK1 | |
| SCHEMBL23749275 | 0.90 | KDR (0.53) | KDRRETMETRIPK3RIPK1 | |
| SCHEMBL23749360 | 0.89 | KDR (0.62) | KDRRETMETRIPK3RIPK1 | |
| SCHEMBL23749435 | 0.89 | KDR (0.69) | KDRRETMETRIPK3RIPK1 | |
| SCHEMBL23771036 | 0.89 | RET (0.55) | KDRRETMETRIPK3RIPK1 | |
| SCHEMBL23749277 | 0.89 | RET (0.58) | KDRRETMETRIPK3RIPK1 | |
| SCHEMBL23749417 | 0.88 | KDR (0.51) | KDRRETMETRIPK3RIPK1 | |
| SCHEMBL23749362 | 0.83 | RET (0.47) | KDRRETMETRIPK3RIPK1 | |
| SCHEMBL23749289 | 0.81 | MST1R (0.62) | KDRRETMETMST1R | |
| SCHEMBL23749440 | 0.79 | RET (0.59) | KDRRETMETMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |