Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18815275 | 0.91 | BTK (0.57) | BTKKLKB1 | |
| SCHEMBL18818271 | 0.88 | BTK (0.62) | BTKKLKB1 | |
| SCHEMBL21953537 | 0.79 | BTK (0.56) | BTKKLKB1 | |
| SCHEMBL23774008 | 0.79 | BTK (0.56) | BTKKLKB1 | |
| SCHEMBL23768970 | 0.79 | BTK (0.66) | BTKKLKB1 | |
| SCHEMBL18816474 | 0.78 | BTK (0.56) | BTKKLKB1 | |
| SCHEMBL23753973 | 0.77 | MAPT (0.45) | BTK | |
| SCHEMBL18795065 | 0.77 | BTK (0.57) | BTKKLKB1 | |
| SCHEMBL23469584 | 0.77 | KLKB1 (0.59) | BTKKLKB1 | |
| SCHEMBL23843083 | 0.76 | BTK (0.47) | BTKKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368524-B1 | HETEROARYLCARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-08-18 | — | — | EP | disclosed |