SCHEMBL23774145

SCHEMBL23774145

CC(=O)NCc1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACACB O00763 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23774139 0.92 ACACB (0.77) ACACB
SCHEMBL23774312 0.91 ACACB (0.76) ACACB
SCHEMBL23774138 0.91 ACACB (0.79) ACACB
SCHEMBL23774300 0.90 ACACB (0.77) ACACB
SCHEMBL23774396 0.90 ACACB (0.75) ACACB
SCHEMBL23774295 0.90 ACACB (0.77) ACACB
SCHEMBL23774158 0.89 ACACB (0.75) ACACB
SCHEMBL23774132 0.89 ACACB (0.77) ACACB
SCHEMBL23774407 0.88 ACACB (0.78) ACACB
SCHEMBL23774254 0.88 ACACB (0.68) ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3194367-B1 TETRAHYDROISOQUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR THE TREATMENT OF OBESITY AND DIABETES BOEHRINGER INGELHEIM INT (DE) 2021-08-18 EP disclosed