Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.65 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17585129 | 0.86 | ACACB (0.73) | ACACB | |
| SCHEMBL23774237 | 0.83 | ACACB (0.69) | ACACB | |
| SCHEMBL23774084 | 0.80 | ACACB (0.67) | ACACB | |
| SCHEMBL17585165 | 0.79 | ACACB (1.00) | ACACB | |
| SCHEMBL23774221 | 0.78 | ACACB (0.60) | ACACB | |
| SCHEMBL17585262 | 0.78 | ACACB (1.00) | ACACB | |
| Hydrochloric Acid SCHEMBL7847183 | 0.77 | HRH3 (0.58) | ACACBHRH3 | |
| SCHEMBL23774343 | 0.77 | ACACB (0.59) | ACACB | |
| SCHEMBL7850640 | 0.77 | HRH3 (0.52) | ACACBMOGAT2HRH3 | |
| Hydrochloric Acid SCHEMBL7846452 | 0.76 | HRH3 (0.52) | ACACBMOGAT2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194367-B1 | TETRAHYDROISOQUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR THE TREATMENT OF OBESITY AND DIABETES | BOEHRINGER INGELHEIM INT (DE) | 2021-08-18 | — | — | EP | disclosed |