Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23774152 | 0.88 | ACACB (0.74) | ACACB | |
| SCHEMBL23774224 | 0.87 | ACACB (0.68) | ACACB | |
| SCHEMBL23774191 | 0.87 | ACACB (0.73) | ACACB | |
| SCHEMBL17585268 | 0.85 | ACACB (1.00) | ACACB | |
| SCHEMBL23774289 | 0.84 | ACACB (0.78) | ACACB | |
| SCHEMBL23774146 | 0.84 | ACACB (0.61) | ACACB | |
| SCHEMBL23774279 | 0.83 | ACACB (0.74) | ACACB | |
| SCHEMBL23774373 | 0.83 | ACACB (0.63) | ACACB | |
| SCHEMBL23774255 | 0.83 | ACACB (0.76) | ACACB | |
| SCHEMBL23774182 | 0.82 | ACACB (0.66) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194367-B1 | TETRAHYDROISOQUINOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR THE TREATMENT OF OBESITY AND DIABETES | BOEHRINGER INGELHEIM INT (DE) | 2021-08-18 | — | — | EP | disclosed |