Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.60 |
| ▸ | GSK3A | P49840 | 4/20 | 0.60 |
| ▸ | CDK1 | P06493 | 3/20 | 0.60 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18813497 | 0.99 | GSK3B (0.59) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL4417355 | 0.83 | GSK3B (0.59) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| Hydrochloric Acid SCHEMBL4425167 | 0.82 | GSK3B (0.59) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL5076231 | 0.77 | GSK3B (0.38) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL29356298 | 0.75 | GSK3B (1.00) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL14672557 | 0.75 | GSK3B (1.00) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL29358332 | 0.75 | GSK3B (1.00) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| SCHEMBL3607008 | 0.75 | PIK3CA (0.33) | GSK3BGSK3ACDK1PIK3CAPIK3CB | |
| SCHEMBL23780644 | 0.75 | GSK3B (0.69) | GSK3BGSK3ACDK1CCNB2CCNB1 | |
| Hydrochloric Acid SCHEMBL25380092 | 0.75 | GSK3B (0.98) | GSK3BGSK3ACDK1CCNB2CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210275595-A1 | NAÏVE HUMAN EMBRYONIC VASCULAR PROGENITOR CELLS AND METHODS OF TREATMENT | THE JOHNS HOPKINS UNIVERSITY | 2021-09-09 | — | — | US | claimed |
| US-20220228111-A1 | NOCICEPTOR DIFFERENTIATION FROM HUMAN PLURIPOTENT STEM CELLS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2022-07-21 | — | — | US | disclosed |