SCHEMBL23781698

SCHEMBL23781698

NC(=O)CC[C@H](N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 6/20 0.49
▸ DPP8 Q6V1X1 3/20 0.49
▸ FAP Q12884 2/20 0.49
▸ DPP9 Q86TI2 2/20 0.49
▸ DPP7 Q9UHL4 2/20 0.49
▸ ACE P12821 4/20 0.43
▸ REN P00797 2/20 0.43
▸ F2 P00734 1/20 0.41
▸ ITGB3 P05106 2/20 0.39
▸ ITGA2B P08514 2/20 0.39
▸ FKBP1A P62942 1/20 0.39
▸ FKBP5 Q13451 1/20 0.39
▸ XIAP P98170 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23781697 1.00 DPP4 (0.49) DPP4DPP8FAPDPP9DPP7
SCHEMBL24011941 1.00 DPP4 (0.49) DPP4DPP8FAPDPP9DPP7
SCHEMBL4337493 0.93 DPP4 (0.45) DPP4DPP8FAPDPP9DPP7
SCHEMBL4337499 0.93 DPP4 (0.45) DPP4DPP8FAPDPP9DPP7
SCHEMBL30193602 0.88 DPP4 (0.43) DPP4DPP8FAPDPP9DPP7
SCHEMBL29426620 0.86 DPP4 (0.54) DPP4DPP8FAPDPP9DPP7
SCHEMBL30775497 0.85 DPP4 (0.56) DPP4DPP8FAPDPP9DPP7
SCHEMBL29615359 0.85 ACE (0.43) DPP4DPP8FAPDPP9DPP7
SCHEMBL29411127 0.84 DPP7 (0.56) DPP4DPP8FAPDPP9DPP7
SCHEMBL29411119 0.84 ACE (0.47) DPP4DPP8FAPDPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240293473-A1 METHODS FOR DIAGNOSIS AND TREATMENT OF TYPE 1 DIABETES Tets, Viktor Veniaminovich (US) 2024-09-05 — — US disclosed
US-11918610-B2 Methods for diagnosis and treatment of type 1 diabetes Tets, Viktor Veniaminovich (US) 2024-03-05 — — US disclosed
CN-117384991-A Preparation method and application of high-bioactivity cyclic peptide 上海中翊日化有限公司 2024-01-12 — — CN disclosed
EP-4135737-A1 LARAZOTIDE DERIVATIVES COMPRISING D-AMINO ACIDS 9 Meters Biopharma, Inc. (US) 2023-02-22 — — EP disclosed
US-20210275600-A1 METHODS FOR DIAGNOSIS AND TREATMENT OF TYPE 1 DIABETES Tets, Viktor Veniaminovich (US) 2021-09-09 — — US disclosed
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