SCHEMBL23783259

SCHEMBL23783259

COc1cc(-c2cn(C)c(=O)c3ccccc23)cc(OC)c1C=O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 18/20 0.64
BRD9 Q9H8M2 4/20 0.64
BRD7 Q9NPI1 4/20 0.64
BRD2 P25440 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30032023 1.00 BRD4 (0.64) BRD4BRD9BRD7BRD2
SCHEMBL25846135 0.91 BRD4 (0.58) BRD4BRD9BRD7BRD2
SCHEMBL23783384 0.86 BRD4 (0.58) BRD4BRD9BRD7BRD2
SCHEMBL30032468 0.85 BRD4 (0.47) BRD4BRD9BRD7BRD2
SCHEMBL22291376 0.85 ERN1 (0.50) BRD4BRD9BRD7BRD2
SCHEMBL23783301 0.85 BRD4 (0.47) BRD4BRD9BRD7BRD2
SCHEMBL31655705 0.85 ERN1 (0.50) BRD4BRD9BRD7BRD2
SCHEMBL27263485 0.85 BRD4 (0.68) BRD4BRD9BRD7BRD2
SCHEMBL26142004 0.85 BRD4 (0.68) BRD4BRD9BRD7BRD2
SCHEMBL21224797 0.84 BRD9 (0.67) BRD4BRD9BRD7BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084081-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2025-03-13 US disclosed
US-12157735-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2024-12-03 US disclosed
US-12049464-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2024-07-30 US disclosed
US-20240051953-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2024-02-15 US disclosed
US-11691972-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2023-07-04 US disclosed
US-11691972-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2023-07-04 US disclosed
US-11691972-B2 Compounds for targeted degradation of BRD9 C4 THERAPEUTICS, INC. (US) 2023-07-04 US disclosed
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2023-03-02 US disclosed
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2023-03-02 US disclosed
EP-4114392-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2023-01-11 EP disclosed
CN-115279370-A Compounds for targeted degradation of BRD9 C4医药公司 2022-11-01 CN disclosed
US-20220098194-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2022-03-31 US disclosed
WO-2021178920-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2021-09-10 WO disclosed
WO-2021178920-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 THERAPEUTICS, INC. (US) 2021-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230060334-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 BRD4 30/4885BRD9 1/4885BRD7 8/4885
US-20220098194-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 BRD4 30/4885BRD9 1/4885BRD7 8/4885
US-12157735-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 BRD4 30/4885BRD9 1/4885BRD7 8/4885
US-12049464-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 BRD4 30/4885BRD9 1/4885BRD7 8/4885
US-20240051953-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 BRD4 30/4885BRD9 1/4885BRD7 8/4885
US-20250084081-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 BRD9, BRD1, BRWD1 BRD4 30/4885BRD9 1/4885BRD7 8/4885
US-11691972-B2 Compounds for targeted degradation of BRD9 BRD9, BRD1, BRWD1 BRD4 17/4885BRD9 1/4885BRD7 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.