SCHEMBL23785490

SCHEMBL23785490

CCCC[C@](C)(CNC(=O)[C@@H]1CCCCN1)Nc1nc(N)nc2cccnc12

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 19/20 0.60
▸ TLR7 Q9NYK1 7/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23785481 1.00 TLR8 (0.60) TLR8TLR7
SCHEMBL23785477 0.98 TLR8 (0.61) TLR8TLR7
SCHEMBL23980715 0.98 TLR8 (0.61) TLR8TLR7
SCHEMBL23785478 0.98 TLR8 (0.61) TLR8TLR7
SCHEMBL23785488 0.95 TLR8 (0.64) TLR8TLR7
SCHEMBL23785468 0.95 TLR8 (0.64) TLR8TLR7
SCHEMBL23785465 0.88 TLR8 (0.58) TLR8TLR7
SCHEMBL23785466 0.88 TLR8 (0.58) TLR8TLR7
SCHEMBL23785491 0.85 TLR8 (0.43) TLR8TLR7
SCHEMBL23785467 0.84 TLR8 (0.58) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3875451-A1 TLR8 AGONIST Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2021-09-08 — — EP disclosed
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