Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782405 | 0.94 | FYN (0.41) | FYNLIPGPTGDR2NPC1PCSK9 | |
| SCHEMBL30173863 | 0.94 | FYN (0.41) | FYNLIPGPTGDR2NPC1PCSK9 | |
| SCHEMBL23792465 | 0.91 | FOLH1 (0.39) | FYNPTGDR2NR1H4ADORA2AADORA1 | |
| SCHEMBL23791794 | 0.90 | FYN (0.38) | FYNLIPGPTGDR2NR1H4PCSK9 | |
| SCHEMBL23792378 | 0.86 | PTGDR2 (0.36) | PTGDR2NR1H4PCSK9MAPTTSHR | |
| SCHEMBL26240327 | 0.85 | FOLH1 (0.41) | FYNPTGDR2NPC1ADORA2AADORA1 | |
| SCHEMBL23782588 | 0.84 | FYN (0.38) | FYNLIPGPTGDR2NPC1PCSK9 | |
| SCHEMBL23791715 | 0.83 | SLC7A5 (0.41) | FYNPTGDR2NR1H4NPC1PCSK9 | |
| SCHEMBL23792710 | 0.82 | PTGDR2 (0.44) | PTGDR2NPC1LMNAMAPT | |
| SCHEMBL23792699 | 0.81 | PTGDR2 (0.39) | PTGDR2NR1H4NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |