Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.42 |
| ▸ | FEN1 | P39748 | 7/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30290029 | 1.00 | NPSR1 (0.44) | NPSR1ALOX5APFEN1HDAC4ANPEP | |
| SCHEMBL23796198 | 0.84 | MRGPRX4 (0.43) | NPSR1ALOX5APFEN1HDAC4CNR1 | |
| SCHEMBL30290051 | 0.84 | MRGPRX4 (0.43) | NPSR1ALOX5APFEN1HDAC4CNR1 | |
| SCHEMBL30290061 | 0.84 | SCN9A (0.51) | MAP4K4 | |
| SCHEMBL23796208 | 0.84 | SCN9A (0.51) | MAP4K4 | |
| SCHEMBL22559108 | 0.84 | NPSR1 (0.42) | NPSR1ANPEPMLYCDKDRMRGPRX4 | |
| SCHEMBL29755055 | 0.84 | NPSR1 (0.42) | NPSR1ANPEPMLYCDKDRMRGPRX4 | |
| SCHEMBL23796108 | 0.83 | MAP4K4 (0.49) | ALOX5APFEN1AKR1C3AKR1C2MAP4K4 | |
| SCHEMBL30289999 | 0.83 | MAP4K4 (0.49) | ALOX5APFEN1AKR1C3AKR1C2MAP4K4 | |
| SCHEMBL23796090 | 0.79 | NPSR1 (0.51) | NPSR1HDAC4CNR1MLYCDMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877356-A1 | BICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| CN-113302175-A | Bicyclic compounds | 维瓦斯治疗公司 | 2021-08-24 | — | — | CN | disclosed |