Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.47 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781606 | 0.77 | NAALAD2 (0.48) | NAALAD2GRNSORT1ALDH1A1RECQL | |
| SCHEMBL31326721 | 0.75 | NAALAD2 (0.44) | NAALAD2GRNSORT1ALDH1A1RECQL | |
| SCHEMBL4447522 | 0.72 | TP53 (0.60) | — | |
| SCHEMBL22718220 | 0.69 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22718218 | 0.69 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL23646039 | 0.69 | NAALAD2 (0.40) | NAALAD2GRNSORT1ALDH1A1RECQL | |
| SCHEMBL10077139 | 0.65 | — | — | |
| SCHEMBL9963345 | 0.65 | CYP1A2 (0.36) | NAALAD2ALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL20652615 | 0.64 | NAALAD2 (0.39) | NAALAD2GRNSORT1ALDH1A1RECQL | |
| SCHEMBL20652620 | 0.63 | NAALAD2 (0.38) | NAALAD2GRNSORT1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877356-A1 | BICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |