Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706841 | 0.84 | CYP1A2 (0.50) | CYP1A2MAPTPOLBHPGDHRH3 | |
| SCHEMBL24040238 | 0.81 | HRH3 (0.40) | HRH3 | |
| SCHEMBL23612752 | 0.79 | HRH3 (0.41) | HRH3 | |
| SCHEMBL23625656 | 0.78 | CYP1A2 (0.43) | CYP1A2MAPTPOLBHPGDHRH3 | |
| SCHEMBL10218782 | 0.78 | CYP1A2 (0.53) | CYP1A2MAPTPOLBHPGDHRH3 | |
| SCHEMBL19087091 | 0.78 | CYP1A2 (0.39) | CYP1A2MAPTPOLBHPGDHRH3 | |
| SCHEMBL23175630 | 0.78 | CYP1A2 (0.53) | CYP1A2MAPTPOLBHPGDHRH3 | |
| SCHEMBL27562576 | 0.77 | MAPT (0.62) | CYP1A2MAPTPOLBHPGDGNAO1 | |
| SCHEMBL22757296 | 0.77 | CYP1A2 (0.42) | CYP1A2MAPTPOLBHPGDHRH3 | |
| SCHEMBL19083183 | 0.77 | CYP1A2 (0.42) | CYP1A2MAPTPOLBHPGDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178920-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 THERAPEUTICS, INC. (US) | 2021-09-10 | — | — | WO | disclosed |