Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 14/20 | 0.57 |
| ▸ | BRD4 | O60885 | 12/20 | 0.57 |
| ▸ | BRD7 | Q9NPI1 | 10/20 | 0.57 |
| ▸ | BRD2 | P25440 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | ATAD2B | Q9ULI0 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25091505 | 0.90 | BRD9 (0.55) | BRD9BRD4BRD7BRD2CYP3A4 | |
| SCHEMBL25092037 | 0.87 | BRD9 (0.57) | BRD9BRD4BRD7BRD2CYP3A4 | |
| Hydrochloric Acid SCHEMBL23783136 | 0.86 | BRD9 (0.56) | BRD9BRD4BRD7BRD2CYP3A4 | |
| SCHEMBL23783302 | 0.84 | BRD4 (0.49) | BRD9BRD4BRD7BRD2CYP3A4 | |
| SCHEMBL33531820 | 0.83 | BRD9 (0.57) | BRD9BRD4BRD7BRD2CYP3A4 | |
| SCHEMBL33530653 | 0.80 | BRD9 (0.58) | BRD9BRD4BRD7BRD2CYP3A4 | |
| SCHEMBL19869762 | 0.79 | BRD9 (0.71) | BRD9BRD4BRD7BRD2CYP3A4 | |
| SCHEMBL33532837 | 0.79 | BRD9 (0.53) | BRD9BRD4BRD7BRD2CYP3A4 | |
| SCHEMBL33532755 | 0.79 | BRD9 (0.57) | BRD9BRD4BRD7BRD2CYP3A4 | |
| SCHEMBL33532847 | 0.78 | BRD4 (0.49) | BRD9BRD4BRD7BRD2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021178920-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 THERAPEUTICS, INC. (US) | 2021-09-10 | — | — | WO | disclosed |