SCHEMBL23801525

SCHEMBL23801525

C=CC(=O)NC(C)CCNC(=O)c1ccc(CN=[N+]=[N-])nc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ GRM5 P41594 1/20 0.37
▸ EPHX2 P34913 5/20 0.36
▸ NAMPT P43490 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ NPC1 O15118 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ KDM4C Q9H3R0 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ CYP2J2 P51589 1/20 0.33
▸ APOBEC3A P31941 1/20 0.33
▸ APOBEC3G Q9HC16 1/20 0.33
▸ HDAC3 O15379 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23810206 0.83 KDM4E (0.41) KDM4ENPC1RAB9AKDM4CAPOBEC3A
SCHEMBL22122703 0.82 GRM5 (0.38) GRM5EPHX2NAMPTKDM4ENPC1
SCHEMBL16560328 0.78 KDM4E (0.41) EPHX2KDM4ELMNANPC1RAB9A
SCHEMBL15285036 0.76 MAOB (0.44) EPHX2KDM4ENPC1RAB9AKDM4C
SCHEMBL23810201 0.76 KDM4E (0.45) KDM4ENPC1RAB9AKDM4CAPOBEC3A
SCHEMBL22149715 0.75 KDM4E (0.40) KDM4ENPC1RAB9AKDM4CAPOBEC3A
SCHEMBL23810141 0.74 KDM4E (0.40) KDM4ENPC1RAB9AKDM4CAPOBEC3A
SCHEMBL19308748 0.74 KMT2A (0.39) KDM4ENPC1RAB9AKDM4CAPOBEC3A
SCHEMBL20804067 0.73 KDM4E (0.38) KDM4ELMNANPC1RAB9AKDM4C
SCHEMBL23255193 0.73 SMN1; SMN2 (0.39) KDM4ENPC1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240300896-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2024-09-12 — — US disclosed
US-11999696-B2 Heterocyclic azide units and their use in polymer coatings ILLUMINA CAMBRIDGE LIMITED (GB) 2024-06-04 — — US disclosed
CN-112672996-B Heterocyclic azide units and their use in polymeric coatings 伊鲁米纳剑桥有限公司 2024-01-05 — — CN disclosed
US-20210284609-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2021-09-16 — — US disclosed
CN-112672996-A Heterocyclic azide units and their use in polymeric coatings 伊鲁米纳剑桥有限公司 2021-04-16 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300896-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS POLL, PCNA, DNMT3A GRM5 2711/4885EPHX2 2220/4885NAMPT 3200/4885
US-20210284609-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS POLL, PCNA, DNMT3A GRM5 2711/4885EPHX2 2220/4885NAMPT 3200/4885
US-11999696-B2 Heterocyclic azide units and their use in polymer coatings POLL, PCNA, DNMT3A GRM5 2711/4885EPHX2 2220/4885NAMPT 3200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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