SCHEMBL23808403

SCHEMBL23808403

CC1C2CCC(O2)[C@H](C)C1c1ccc(NC(=O)c2nc(C#N)c[nH]2)c(C2=CCC(C)(C)CC2)c1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 6/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23808448 1.00 CSF1R (0.54) CSF1R
SCHEMBL23808447 1.00 CSF1R (0.54) CSF1R
SCHEMBL19773470 1.00 CSF1R (0.54) CSF1R
SCHEMBL19264289 0.97 CSF1R (0.52) CSF1R
SCHEMBL23808414 0.92 CSF1R (0.49) CSF1R
SCHEMBL23808532 0.92 CSF1R (0.49) CSF1R
SCHEMBL23808704 0.91 CSF1R (0.54) CSF1R
SCHEMBL19264617 0.91 CSF1R (0.54) CSF1R
SCHEMBL23808412 0.91 CSF1R (0.54) CSF1R
SCHEMBL19264247 0.89 CSF1R (0.49) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3208269-B1 INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA NV (BE) 2021-09-15 — — EP disclosed
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