Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086111 | 0.86 | MGAM (0.56) | MGAMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19021347 | 0.82 | MGAM (0.51) | MGAMKDM4EHCAR2ALDH1A1LMNA | |
| SCHEMBL19021373 | 0.81 | MGAM (0.50) | MGAMGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL18987456 | 0.81 | MGAM (0.50) | MGAMKDM4EHCAR2ALDH1A1LMNA | |
| SCHEMBL19021386 | 0.81 | MGAM (0.50) | MGAMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24358304 | 0.81 | MGAM (0.50) | MGAMHCAR2PSMD14PDGFRBPDGFRA | |
| Bromide SCHEMBL18987913 | 0.81 | MGAM (0.50) | MGAMKDM4EHCAR2ALDH1A1LMNA | |
| SCHEMBL8519849 | 0.79 | MGAM (0.63) | MGAMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1645675 | 0.78 | MGAM (0.47) | MGAMHCAR2PSMD14PDGFRBPDGFRA | |
| SCHEMBL18987942 | 0.77 | MGAM (0.50) | MGAMHCAR2PSMD14PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390384-B1 | QUINOLINE-3-CARBOXAMIDES AS H-PGDS INHIBITORS | ASTEX THERAPEUTICS LTD (GB) | 2021-09-15 | — | — | EP | disclosed |