Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 7/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.45 |
| ▸ | BPTF | Q12830 | 2/20 | 0.45 |
| ▸ | BRD1 | O95696 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.45 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084337 | 1.00 | KAT2B (0.45) | KAT2BBRD9BPTFBRD1ACHE | |
| SCHEMBL23815809 | 1.00 | KAT2B (0.45) | KAT2BBRD9BPTFBRD1ACHE | |
| SCHEMBL19122233 | 1.00 | KAT2B (0.45) | KAT2BBRD9BPTFBRD1ACHE | |
| SCHEMBL23682832 | 1.00 | KAT2B (0.45) | KAT2BBRD9BPTFBRD1ACHE | |
| SCHEMBL9910977 | 0.83 | BRD4 (0.53) | BRD4SRD5A1DRD2DRD1DRD4 | |
| SCHEMBL19121359 | 0.83 | TSHR (0.39) | KAT2BBRD9 | |
| SCHEMBL14012482 | 0.79 | BRD4 (0.47) | KAT2BBRD9BPTFBRD1ACHE | |
| SCHEMBL11310532 | 0.79 | BRD4 (0.43) | KAT2BBRD9BRD4DRD2DRD1 | |
| SCHEMBL11310485 | 0.79 | BRD4 (0.43) | KAT2BBRD9BRD4DRD2DRD1 | |
| SCHEMBL11310351 | 0.79 | BRD4 (0.43) | KAT2BBRD9BRD4DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283265-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283265-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | NEDD4, CBL, UBQLN2 | KAT2B 2513/4885BRD9 2024/4885BPTF 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.