Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23816068 | 0.87 | BTK (0.44) | BTKLCK | |
| SCHEMBL30151517 | 0.87 | BTK (0.41) | BTKLCK | |
| SCHEMBL30063476 | 0.87 | BTK (0.44) | BTKLCK | |
| SCHEMBL23816316 | 0.85 | BTK (0.38) | BTK | |
| Hydrochloric Acid SCHEMBL30064702 | 0.85 | BTK (0.38) | BTK | |
| Hydrochloric Acid SCHEMBL26114064 | 0.85 | BTK (0.38) | BTK | |
| Hydrochloric Acid SCHEMBL26114060 | 0.85 | BTK (0.38) | BTK | |
| SCHEMBL23816213 | 0.84 | BTK (0.41) | BTKLCK | |
| SCHEMBL30063464 | 0.84 | BTK (0.41) | BTKLCK | |
| SCHEMBL30063405 | 0.84 | BTK (0.41) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021180103-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2021-09-16 | — | — | WO | disclosed |