⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23826837 | 1.00 | — | — | |
| SCHEMBL28900028 | 0.86 | — | — | |
| SCHEMBL31336522 | 0.84 | USP2 (0.38) | — | |
| SCHEMBL29366691 | 0.84 | USP2 (0.38) | — | |
| SCHEMBL31566827 | 0.80 | USP30 (0.41) | — | |
| SCHEMBL18322988 | 0.77 | — | — | |
| SCHEMBL31184416 | 0.77 | USP2 (0.37) | — | |
| SCHEMBL18322986 | 0.77 | — | — | |
| SCHEMBL29959213 | 0.77 | USP2 (0.37) | — | |
| SCHEMBL18319615 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| EP-3882239-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2021-09-22 | — | — | EP | disclosed |
| CN-113302184-A | 1,3, 4-oxadiazolinone compounds and drugs | 日本新药株式会社 | 2021-08-24 | — | — | CN | disclosed |