SCHEMBL23827201

SCHEMBL23827201

COc1ccc(C(OC[C@@]23CN(C(=O)N(C)C)[C@@H]([C@H](n4cc(C)c(=O)[nH]c4=O)O2)[C@@H]3OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK2 O00142 5/20 0.30
TK1 P04183 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23827237 0.93 TK2 (0.33) TK2TK1
SCHEMBL23827247 0.93 TK2 (0.31) TK2TK1
SCHEMBL31634930 0.93 TK2 (0.33) TK2TK1
SCHEMBL3033795 0.92 TK2 (0.33) TK2TK1
SCHEMBL4337905 0.91
SCHEMBL23827208 0.90 TK2 (0.31) TK2TK1
SCHEMBL21124239 0.90
SCHEMBL23827288 0.89 TK2 (0.30) TK2TK1
SCHEMBL23891812 0.88
SCHEMBL23827335 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12338265-B2 Crosslinked artificial nucleic acid ALNA MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-06-24 US claimed
CN-119119156-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-12-13 CN claimed
CN-117964673-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN claimed
US-20220002336-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA MITSUBISHI TANABE PHARMA CORPORATION (JP) 2022-01-06 US claimed
EP-3881851-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA Mitsubishi Tanabe Pharma Corporation (JP) 2021-09-22 EP claimed
US-20250340584-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-11-06 US disclosed
US-12338265-B2 Crosslinked artificial nucleic acid ALNA MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-06-24 US disclosed
CN-119119156-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-12-13 CN disclosed
CN-112996522-B Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-09-20 CN disclosed
CN-117964674-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
CN-117964673-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
EP-4275690-A2 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA Mitsubishi Tanabe Pharma Corporation (JP) 2023-11-15 EP disclosed
EP-4275689-A2 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA Mitsubishi Tanabe Pharma Corporation (JP) 2023-11-15 EP disclosed
US-20220002336-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA MITSUBISHI TANABE PHARMA CORPORATION (JP) 2022-01-06 US disclosed
EP-3881851-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA Mitsubishi Tanabe Pharma Corporation (JP) 2021-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340584-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA POLN, DDX21, MUS81 TK2 2564/4885TK1 2068/4885
US-20220002336-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA POLN, DDX21, MUS81 TK2 2564/4885TK1 2068/4885
US-12338265-B2 Crosslinked artificial nucleic acid ALNA POLN, DDX21, MUS81 TK2 2564/4885TK1 2068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.