Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113232 | 0.92 | GAA (0.66) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL15277871 | 0.89 | GAA (0.69) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL1976156 | 0.89 | GAA (0.69) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL1976632 | 0.89 | GAA (0.69) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL3107873 | 0.89 | GAA (0.69) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL3113240 | 0.89 | GAA (0.69) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL3113249 | 0.88 | GAA (0.71) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL3095198 | 0.83 | GAA (0.55) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL1973534 | 0.82 | GAA (0.56) | GAAMAPK1MAPTALDH1A1ALOX15 | |
| SCHEMBL16689448 | 0.81 | GAA (0.64) | GAAMAPK1MAPTALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | claimed |