Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23828675 | 0.95 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| SCHEMBL12643455 | 0.91 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| SCHEMBL23828670 | 0.91 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| Hydrochloric Acid SCHEMBL30330403 | 0.90 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| Fluoride SCHEMBL30330556 | 0.90 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| Hydrochloric Acid SCHEMBL30330420 | 0.90 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| SCHEMBL2116369 | 0.88 | S1PR1 (0.45) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| SCHEMBL2116370 | 0.88 | S1PR1 (0.45) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| Hydrochloric Acid SCHEMBL30330555 | 0.88 | S1PR1 (0.56) | S1PR1S1PR3S1PR5S1PR4HSD17B10 | |
| Fluoride SCHEMBL30330897 | 0.88 | S1PR1 (0.56) | S1PR1S1PR3S1PR5S1PR4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306008-B2 | Working medium and water treatment system | KABUSHIKI KAISHA TOSHIBA (JP) | 2022-04-19 | — | — | US | claimed |
| US-20210292194-A1 | WORKING MEDIUM AND WATER TREATMENT SYSTEM | KABUSHIKI KAISHA TOSHIBA (JP) | 2021-09-23 | — | — | US | claimed |
| US-11306008-B2 | Working medium and water treatment system | KABUSHIKI KAISHA TOSHIBA (JP) | 2022-04-19 | — | — | US | disclosed |
| US-20210292194-A1 | WORKING MEDIUM AND WATER TREATMENT SYSTEM | KABUSHIKI KAISHA TOSHIBA (JP) | 2021-09-23 | — | — | US | disclosed |