Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831650 | 0.91 | MEN1 (0.47) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL23831605 | 0.87 | MEN1 (0.53) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL30105198 | 0.87 | MEN1 (0.44) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL23831687 | 0.87 | MEN1 (0.44) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL30104932 | 0.87 | MEN1 (0.53) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL30105361 | 0.86 | MEN1 (0.61) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL30792348 | 0.86 | TRPV1 (0.54) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL23831977 | 0.86 | TRPV1 (0.54) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL23831796 | 0.86 | MEN1 (0.61) | MEN1KMT2AMAPTRAB9ATRPV1 | |
| SCHEMBL23831714 | 0.85 | MEN1 (0.48) | MEN1KMT2AMAPTRAB9ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021185391-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2021-09-23 | — | — | WO | disclosed |