Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.71 |
| ▸ | SCN1A | P35498 | 4/20 | 0.71 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22746268 | 0.88 | SCN1A (0.57) | SCN3ASCN1ASCN2APGRMAPT | |
| Prilocaine SCHEMBL30487874 | 0.83 | SCN1A (1.00) | SCN3ASCN1ASCN2APGRMAPT | |
| Prilocaine SCHEMBL1813632 | 0.83 | SCN1A (1.00) | SCN3ASCN1ASCN2APGRMAPT | |
| SCHEMBL28957057 | 0.83 | SCN3A (0.50) | SCN3ASCN1ASCN2APGRMAPT | |
| Prilocaine SCHEMBL25467 | 0.83 | SCN1A (1.00) | SCN3ASCN1ASCN2APGRMAPT | |
| Prilocaine SCHEMBL866149 | 0.83 | SCN1A (1.00) | SCN3ASCN1ASCN2APGRMAPT | |
| Prilocaine SCHEMBL25468 | 0.83 | SCN1A (1.00) | SCN3ASCN1ASCN2APGRMAPT | |
| Prilocaine SCHEMBL31333079 | 0.83 | SCN1A (1.00) | SCN3ASCN1ASCN2APGRMAPT | |
| Prilocaine SCHEMBL330180 | 0.82 | HPGD (1.00) | SCN3ASCN1ASCN2APGRMAPT | |
| Prilocaine SCHEMBL9453293 | 0.82 | HPGD (1.00) | SCN3ASCN1ASCN2APGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11123284-B2 | Method of treating disease | CREWS THOMAS M (US) | 2021-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11123284-B2 | Method of treating disease | COXFA4L2, ASAH2, OTC | SCN3A 1010/4885SCN1A 1405/4885SCN2A 2081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.