Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17337492 | 0.89 | TDP1 (0.36) | TDP1ATMALDH1A1CASP3SENP8 | |
| SCHEMBL17337490 | 0.89 | TDP1 (0.36) | TDP1ATMALDH1A1CASP3SENP8 | |
| SCHEMBL23837419 | 0.89 | TDP1 (0.33) | TDP1ATMMAPT | |
| SCHEMBL23837530 | 0.88 | — | — | |
| SCHEMBL23129881 | 0.82 | TDP1 (0.39) | TDP1ATMALDH1A1HPGDMAPT | |
| SCHEMBL17347749 | 0.82 | TDP1 (0.39) | TDP1ATMALDH1A1HPGDMAPT | |
| SCHEMBL23837541 | 0.81 | TSHR (0.34) | TDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL17347701 | 0.80 | TDP1 (0.40) | TDP1ATMALDH1A1HPGDMAPT | |
| SCHEMBL23129642 | 0.80 | TDP1 (0.40) | TDP1ATMALDH1A1HPGDMAPT | |
| SCHEMBL23129978 | 0.80 | TDP1 (0.37) | TDP1ATMALDH1A1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882252-A1 | BETA-LACTAMASE INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |