Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.85 |
| ▸ | ATRIP | Q8WXE1 | 20/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18109996 | 0.92 | ATR (1.00) | ATRATRIPKCNH2 | |
| SCHEMBL20082114 | 0.89 | ATR (0.84) | ATRATRIPKCNH2 | |
| SCHEMBL17501500 | 0.86 | ATR (1.00) | ATRATRIPKCNH2 | |
| SCHEMBL30140516 | 0.83 | ATR (1.00) | ATRATRIPKCNH2 | |
| SCHEMBL17527543 | 0.83 | ATR (1.00) | ATRATRIPKCNH2 | |
| SCHEMBL17501556 | 0.83 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501581 | 0.83 | ATR (1.00) | ATRATRIPKCNH2 | |
| SCHEMBL17501625 | 0.83 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501192 | 0.83 | ATR (0.82) | ATRATRIPKCNH2 | |
| SCHEMBL17501513 | 0.82 | ATR (1.00) | ATRATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395818-B1 | 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | Bayer Pharma AG (DE) | 2021-09-22 | — | — | EP | disclosed |