Sugi Predict

Sugi Predict / Compounds / SCHEMBL23838475

SCHEMBL23838475

SCHEMBL23838475

C=Cc1c(/C=C\C)c2ccc3c4ccccc4n(-c4ccccc4)c3c2n1-c1ccc(-n2c3ccccc3c3ccc4c5ccccc5n(-c5ccccc5)c4c32)cc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ PTPN1 P18031 1/20 0.32
▸ FOLH1 Q04609 1/20 0.32
▸ MAPK8 P45983 2/20 0.32
▸ MAPK9 P45984 1/20 0.31
▸ PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21117110 0.99 KDM4E (0.42) KDM4EATML3MBTL1PTPN1FOLH1
SCHEMBL21566363 0.94 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL24988448 0.94 KDM4E (0.36) KDM4EATML3MBTL1PTPN1
SCHEMBL22007507 0.93 KDM4E (0.39) KDM4EATML3MBTL1PTPN1
SCHEMBL19867970 0.93 KDM4E (0.38) KDM4EATML3MBTL1PTPN1
SCHEMBL21139950 0.90 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL24277812 0.89 KDM4E (0.33) KDM4EATML3MBTL1FOLH1
SCHEMBL21498182 0.87 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL24088792 0.87 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL24006405 0.86 KDM4E (0.34) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3882254-A1 PHOSPHORESCENT HOMOLEPTIC TRIS-[DEUTERATED-2(2-PYRIDINYL)PHENYL]-IRIDIUM COMPLEXES FOR USE IN LIGHT-EMITTING DEVICES Universal Display Corporation (US) 2021-09-22 — — EP disclosed