SCHEMBL23839628

SCHEMBL23839628

c1ccc(-c2ccc(-c3cc(-c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4cc(-c6ccc7ccc8cccc9ccc6c7c89)ccc4-5)nc(-c4ccccc4)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.40
KMT2A Q03164 8/20 0.40
HPGD P15428 8/20 0.40
ALDH1A1 P00352 7/20 0.40
MAPT P10636 7/20 0.40
KDM4E B2RXH2 5/20 0.40
LMNA P02545 2/20 0.40
GLA P06280 1/20 0.40
NTSR1 P30989 1/20 0.39
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
MAOB P27338 3/20 0.34
MAOA P21397 3/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23839584 0.99 MEN1 (0.41) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839648 0.98 MEN1 (0.39) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839650 0.98 MEN1 (0.39) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839799 0.97 MEN1 (0.37) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839779 0.97 MEN1 (0.40) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839687 0.96 MAPT (0.40) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839585 0.95 MEN1 (0.41) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839790 0.93 MEN1 (0.35) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839800 0.93 MEN1 (0.37) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL23839576 0.92 MEN1 (0.35) MEN1KMT2AHPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3882238-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND Idemitsu Kosan Co.,Ltd. (JP) 2021-09-22 EP disclosed