Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.58 |
| ▸ | GNRHR | P30968 | 2/20 | 0.57 |
| ▸ | MC4R | P32245 | 2/20 | 0.54 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.54 |
| ▸ | NMBR | P28336 | 1/20 | 0.54 |
| ▸ | GRPR | P30550 | 1/20 | 0.54 |
| ▸ | MC5R | P33032 | 1/20 | 0.53 |
| ▸ | MC3R | P41968 | 1/20 | 0.53 |
| ▸ | MC1R | Q01726 | 1/20 | 0.53 |
| ▸ | GLP1R | P43220 | 1/20 | 0.53 |
| ▸ | GCGR | P47871 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619597 | 0.95 | C5AR1 (0.67) | C5AR1PTGS1KISS1RCXCR4GNRHR | |
| SCHEMBL29942618 | 0.93 | C5AR1 (0.64) | C5AR1PTGS1KISS1RCXCR4GNRHR | |
| SCHEMBL30271248 | 0.93 | C5AR1 (0.64) | C5AR1PTGS1KISS1RCXCR4GNRHR | |
| SCHEMBL29459909 | 0.92 | C5AR1 (0.67) | C5AR1PTGS1KISS1RCXCR4GNRHR | |
| SCHEMBL31351848 | 0.91 | C5AR1 (0.68) | C5AR1PTGS1CXCR4GNRHRMC4R | |
| SCHEMBL29391299 | 0.91 | C5AR1 (0.68) | C5AR1PTGS1CXCR4GNRHRMC4R | |
| Triptorelin SCHEMBL5079698 | 0.90 | PTGS1 (0.74) | C5AR1PTGS1KISS1RCXCR4GNRHR | |
| Triptorelin SCHEMBL16815056 | 0.90 | PTGS1 (0.74) | C5AR1PTGS1KISS1RCXCR4GNRHR | |
| Triptorelin SCHEMBL22289009 | 0.90 | PTGS1 (0.74) | C5AR1PTGS1KISS1RCXCR4GNRHR | |
| Triptorelin SCHEMBL1371630 | 0.90 | PTGS1 (0.74) | C5AR1PTGS1KISS1RCXCR4GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210290787-A1 | MACROCYCLE CONJUGATES | LUMIPHORE, INC. | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210290787-A1 | MACROCYCLE CONJUGATES | FOLH1, KLK3, CD47 | C5AR1 1929/4885PTGS1 3282/4885KISS1R 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.