Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PDE6D | O43924 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.47 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22599796 | 0.90 | ESR1 (0.52) | ESR1ESR2ALDH1A1PDE6DALDH2 | |
| SCHEMBL26149298 | 0.83 | ESR1 (0.43) | ESR1ESR2ALDH1A1PDE6DALDH2 | |
| SCHEMBL23266608 | 0.83 | ESR1 (0.58) | ESR1ESR2ALDH1A1PDE6DALDH2 | |
| SCHEMBL23840264 | 0.83 | GAA (0.43) | ESR1ESR2ALDH1A1POLBHTT | |
| SCHEMBL22599753 | 0.83 | ESR1 (0.43) | ESR1ESR2ALDH1A1PDE6DALDH2 | |
| SCHEMBL28382155 | 0.83 | GSR (0.55) | ESR1ESR2ALDH1A1PDE6DALDH2 | |
| SCHEMBL12854036 | 0.82 | ESR1 (0.56) | ESR1ESR2ALDH1A1PDE6DALDH2 | |
| SCHEMBL2462367 | 0.82 | ESR1 (0.56) | ESR1ESR2ALDH1A1PDE6DALDH2 | |
| SCHEMBL13299515 | 0.82 | TSHR (0.68) | ESR1ESR2ALDH1A1PDE6DALDH2 | |
| SCHEMBL23266684 | 0.81 | ESR1 (0.52) | ESR1ESR2ALDH1A1PDE6DALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-18 | — | — | US | disclosed |
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021185712-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, CTCF, EED | ESR1 47/4885ESR2 159/4885ALDH1A1 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.