Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22600096 | 0.83 | CNR2 (0.38) | ADORA2ASMN1; SMN2MAPK1TSHRCNR2 | |
| SCHEMBL22600025 | 0.78 | TSHR (0.39) | ADORA2ASMN1; SMN2MAPK1TSHRCNR2 | |
| SCHEMBL24179382 | 0.76 | ADORA2A (0.39) | ADORA2ASMN1; SMN2MAPK1TSHRCNR2 | |
| SCHEMBL14124486 | 0.76 | TSHR (0.45) | ADORA2ASMN1; SMN2MAPK1TSHRCNR2 | |
| SCHEMBL14124469 | 0.76 | TSHR (0.45) | ADORA2ASMN1; SMN2MAPK1TSHRCNR2 | |
| SCHEMBL10041258 | 0.74 | MAPK1 (0.49) | ADORA2ASMN1; SMN2MAPK1TSHRCNR2 | |
| SCHEMBL10041280 | 0.74 | MAPK1 (0.41) | ADORA2ASMN1; SMN2MAPK1TSHRTP53 | |
| SCHEMBL25878270 | 0.74 | CNR2 (0.54) | SMN1; SMN2MAPK1TSHRCNR2TP53 | |
| SCHEMBL12026134 | 0.73 | MAPK1 (0.61) | SMN1; SMN2MAPK1TSHRCNR2SLC22A12 | |
| SCHEMBL10041277 | 0.72 | MAPK1 (0.48) | ADORA2AMAPK1TSHRCNR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-18 | — | — | US | disclosed |
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021185712-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, CTCF, EED | ADORA2A 2953/4885SMN1; SMN2 4714/4885MAPK1 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.