Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18529828 | 0.80 | AOC3 (0.50) | AOC3L3MBTL1IGF1RPKMCHRM2 | |
| SCHEMBL31476413 | 0.80 | AOC3 (0.50) | AOC3L3MBTL1IGF1RPKMCHRM2 | |
| SCHEMBL12443488 | 0.79 | CNR2 (0.52) | AOC3L3MBTL1MEN1KMT2APKM | |
| SCHEMBL2093768 | 0.79 | AOC3 (0.59) | AOC3L3MBTL1PKMCHRM2CHRM1 | |
| SCHEMBL6598474 | 0.78 | IGF1R (0.50) | AOC3L3MBTL1IGF1RPKMCHRM2 | |
| SCHEMBL5511034 | 0.77 | TOP2A (0.48) | IDO1TOP2ATOP2B | |
| SCHEMBL4822561 | 0.74 | AOC3 (0.54) | AOC3L3MBTL1PKMCHRM2CHRM1 | |
| SCHEMBL27686957 | 0.74 | AOC3 (0.54) | AOC3L3MBTL1PKMCHRM2CHRM1 | |
| SCHEMBL477338 | 0.74 | AOC3 (0.54) | AOC3L3MBTL1PKMCHRM2CHRM1 | |
| SCHEMBL6866452 | 0.73 | AOC3 (0.47) | AOC3L3MBTL1PKMCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |