Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832995 | 0.96 | AAK1 (0.42) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23832993 | 0.96 | AAK1 (0.42) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22526179 | 0.96 | AAK1 (0.42) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23833098 | 0.95 | AAK1 (0.39) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22526125 | 0.95 | AAK1 (0.39) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23833191 | 0.95 | AAK1 (0.39) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23833330 | 0.95 | AAK1 (0.40) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23833333 | 0.95 | AAK1 (0.40) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23833128 | 0.94 | AAK1 (0.41) | AAK1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23833241 | 0.94 | AAK1 (0.41) | AAK1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |