Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | TRHR | P34981 | 3/20 | 0.54 |
| ▸ | CMA1 | P23946 | 8/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832966 | 0.86 | ACE (0.55) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL23832967 | 0.86 | ACE (0.55) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL6078759 | 0.84 | ACE (0.61) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL6078614 | 0.84 | ACE (0.61) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL5900836 | 0.82 | ACE (0.77) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL22409423 | 0.82 | ACE (0.77) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL5900839 | 0.82 | ACE (0.77) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL3692081 | 0.82 | ACE (0.77) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL3692085 | 0.82 | ACE (0.77) | ACECMA1F2PRSS1KLK5 | |
| SCHEMBL8378100 | 0.82 | ACE (0.77) | ACECMA1F2PRSS1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |