Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 19/20 | 0.56 |
| ▸ | CCND1 | P24385 | 18/20 | 0.56 |
| ▸ | CCND3 | P30281 | 13/20 | 0.56 |
| ▸ | CCND2 | P30279 | 9/20 | 0.56 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.55 |
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.55 |
| ▸ | CDK9 | P50750 | 4/20 | 0.55 |
| ▸ | CDK1 | P06493 | 2/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.51 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25595157 | 0.87 | CDK4 (0.46) | CDK4CCND1CCND3CCND2CDK6 | |
| SCHEMBL19294159 | 0.83 | CDK4 (0.64) | CDK4CCND1CCND3CCND2CDK6 | |
| SCHEMBL23913121 | 0.82 | CDK4 (0.61) | CDK4CCND1CCND3CCND2CDK6 | |
| SCHEMBL31607947 | 0.82 | CDK4 (0.44) | CDK4CCND1CCND3CCND2CDK6 | |
| SCHEMBL28404189 | 0.82 | CDK4 (0.63) | CDK4CCND1CCND3CCND2CDK6 | |
| SCHEMBL31607889 | 0.81 | CYP1A2 (0.50) | CDK4CCND1CCND3CCND2CDK6 | |
| SCHEMBL31475428 | 0.81 | CYP1A2 (0.50) | CDK4CCND1CCND3CCND2CDK2 | |
| SCHEMBL18788069 | 0.81 | CDK4 (0.62) | CDK4CCND1CCND3CCND2CDK6 | |
| SCHEMBL4833350 | 0.81 | CDK4 (0.62) | CDK4CCND1CCND3CCND2CDK6 | |
| SCHEMBL29671046 | 0.81 | CDK4 (0.62) | CDK4CCND1CCND3CCND2CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514796-A1 | CDK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | OnQuality Pharmaceuticals China Ltd. (CN) | 2025-03-05 | — | — | EP | claimed |
| WO-2023207875-A1 | CDK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | ONQUALITY PHARMACEUTICALS CHINA LTD. (CN) | 2023-11-02 | — | — | WO | claimed |
| EP-4514796-A1 | CDK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | OnQuality Pharmaceuticals China Ltd. (CN) | 2025-03-05 | — | — | EP | disclosed |
| CN-118451078-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2023207875-A1 | CDK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | ONQUALITY PHARMACEUTICALS CHINA LTD. (CN) | 2023-11-02 | — | — | WO | disclosed |
| US-20230174548-A1 | SYMBIOTIC PRODRUGS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-06-08 | — | — | US | disclosed |
| US-20230174548-A1 | SYMBIOTIC PRODRUGS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-06-08 | — | — | US | disclosed |
| WO-2021188855-A1 | SYMBIOTIC PRODRUGS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2021-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174548-A1 | SYMBIOTIC PRODRUGS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | NFKBIA, NFRKB, IKBKB | CDK4 879/4885CCND1 3067/4885CCND3 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.