SCHEMBL23847741

SCHEMBL23847741

Nc1ncnn2c(C3CCCCC3)nc(-c3ccc(Oc4ccccc4)cc3F)c12

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23834486 0.90 TNK2 (0.61) TNK2
SCHEMBL29913547 0.90 TNK2 (0.61) TNK2
SCHEMBL29913551 0.90 TNK2 (0.61) TNK2
SCHEMBL29913388 0.90 TNK2 (0.61) TNK2
SCHEMBL23625283 0.89 TNK2 (0.76) TNK2
SCHEMBL23834588 0.87 TNK2 (0.57) TNK2
SCHEMBL23834478 0.86 TNK2 (0.56) TNK2
SCHEMBL23834476 0.86 TNK2 (0.56) TNK2
SCHEMBL23834488 0.86 TNK2 (0.56) TNK2
SCHEMBL30054417 0.86 TNK2 (0.56) TNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021188417-A1 COMPOUNDS FOR TREATING OR INHIBITING RECURRENCE OF ACUTE MYELOID LEUKEMIA FLASH THERAPEUTICS, LLC (US) 2021-09-23 WO disclosed