SCHEMBL2384775

SCHEMBL2384775

CNc1ccc(I)cc1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.64
PTPN2 P17706 1/20 0.64
PTPN1 P18031 1/20 0.64
PTPRA P18433 1/20 0.64
PTPRB P23467 1/20 0.64
PTPRE P23469 1/20 0.64
PTPN6 P29350 1/20 0.64
MAPT P10636 3/20 0.56
CA12 O43570 1/20 0.51
CA7 P43166 1/20 0.51
IDO1 P14902 2/20 0.49
KDM4C Q9H3R0 1/20 0.49
MAP2K1 Q02750 7/20 0.45
MAP2K2 P36507 2/20 0.45
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6706077 0.83 KDM4E (0.64) PTPRCPTPN2PTPN1PTPRAPTPRB
SCHEMBL20466336 0.82 PTPRC (0.66) PTPRCPTPN2PTPN1PTPRAPTPRB
SCHEMBL11635389 0.82 MAPT (0.58) PTPRCPTPN2PTPN1PTPRAPTPRB
SCHEMBL3898806 0.81 PTPRC (0.60) PTPRCPTPN2PTPN1PTPRAPTPRB
SCHEMBL6223409 0.81 KDM4E (0.58) PTPRCPTPN2PTPN1PTPRAPTPRB
Hydrochloric Acid SCHEMBL4741934 0.81 PTPRC (0.64) PTPRCPTPN2PTPN1PTPRAPTPRB
SCHEMBL3887267 0.79 PTPRC (0.66) PTPRCPTPN2PTPN1PTPRAPTPRB
SCHEMBL5678007 0.79 IDO1 (0.70) PTPRCPTPN2PTPN1PTPRAPTPRB
SCHEMBL17938282 0.78 MAPT (0.57) MAPTKDM4CKDM4EALDH1A1GAA
SCHEMBL11412178 0.78 MEN1 (0.58) MAPTCA12CA7KDM4CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024176701-A1 RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, COMPOUND, AND POLYMER COMPOUND 東京応化工業株式会社 2024-08-29 WO disclosed
WO-2020071550-A1 CDK8 INHIBITOR AND USE OF SAME 京都薬品工業株式会社 2020-04-09 WO disclosed
US-8841334-B2 Compounds as cannabinoid receptor ligands and uses thereof ABBVIE INC. (US) 2014-09-23 US disclosed
EP-1960363-B1 QUINOLONE BASED COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS AND USES THEREOF AMGEN INC (US) 2014-01-22 EP disclosed
EP-1960363-B1 QUINOLONE BASED COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS AND USES THEREOF AMGEN INC (US) 2014-01-22 EP disclosed
EP-2142509-B1 QUINOLONES AND AZAQUINOLONES THAT INHIBIT PROLYL HYDROXYLASE AMGEN INC (US) 2013-12-04 EP disclosed
US-8546583-B2 Pain, inflammatory or immune disorders, neurological disorders, cancers of the immune system, respiratory disorders, cardiovascular disorders, neuroprotection; e.g. 5-chloro-N-[(2Z)-5-(1-hydroxy-1-methylethyl)-3-[((cis)-3-methoxycyclobutyl)methyl]-4-methyl-1,3-thiazol-2(3H)-ylidene]-2-methoxybenzamide ABBVIE INC. (US) 2013-10-01 US disclosed
EP-2222165-B1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF ABBVIE INC (US) 2013-07-31 EP disclosed
US-8349868-B2 Azaquinolones that inhibit prolyl hydroxylase AMGEN INC. (US) 2013-01-08 US disclosed
CN-102442970-A Thiazole compounds as cannabinoid receptor ligands and uses thereof ABBOTT LAB 2012-05-09 CN disclosed
EP-0917462-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1999-05-26 EP disclosed
WO-1998026664-A1 FUNGICIDAL QUINAZOLINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-25 WO disclosed
WO-1998004247-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1998-02-05 WO disclosed
US-5674863-A BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR GENENTECH, INC. (US) 1997-10-07 US disclosed
US-5674865-A BENZODIAZEPINEDIONE DERIVATIVE; FIBRINOGIN BINDING INHIBITOR GENENTECH, INC. (US) 1997-10-07 US disclosed
US-5663166-A ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING GENENTECH, INC. (US) 1997-09-02 US disclosed
US-5565449-A PLATELET AGGREGATION INHIBITORS GENENTECH, INC. (US) 1996-10-15 US disclosed
EP-0610334-B1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR GENENTECH INC (US) 1996-01-24 EP disclosed
EP-0610334-A1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. GENENTECH INC (US) 1994-08-17 EP disclosed
WO-1993008174-A1 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR GENENTECH, INC. (US) 1993-04-29 WO disclosed